The EOSC-ENTRUST project has published a report summarising the revised Trusted Research Environment (TRE) driver requirements and challenges for federated data access in TREs.
EOSC-ENTRUST has four drivers, or use cases, that demonstrate different aspects of TRE functionality across a range of sectors requiring secure and reliable handling of sensitive data. The drivers focus on federated human genomics, transnational social science data, clinical trial data and public-private interactions between TRE in health and environmental data.
The project held four online show-and-tell workshops, where each driver demonstrated the prototype process of data access and use within its TRE, highlighting technical and procedural requirements. A summary session was held to consolidate cross-driver challenges and requirements and provide recommendations for the TRE framework.
The outcomes of the workshops formed the basis of the report and were further discussed in an EOSC-ENTRUST evaluation and adoption workshop. Major challenges for the federation framework, such as inconsistent AAAI infrastructure and fragmented legal and technical frameworks, were identified and will be addressed in the second EOSC-ENTRUST Blueprint, due this year.
More information
- Read the report on revised driver requirements for TREs
- Second EOSC-ENTRUST evaluation and adoption workshop slides
- More about EOSC-ENTRUST Drivers
Posted: 16 October 2025
